Cell Proliferation and Apoptosis by D. Hughes

Cover of: Cell Proliferation and Apoptosis | D. Hughes

Published by BIOS Scientific Publ .

Written in English

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  • Cellular biology,
  • Life Sciences - Cytology,
  • Cytology,
  • Science,
  • Science/Mathematics,
  • Oncology,
  • Research & Methodology,
  • Science / Biotechnology,
  • Cell Division,
  • Life Sciences - Biology - General,
  • Apoptosis,
  • Cell proliferation

Book details

The Physical Object
Number of Pages344
ID Numbers
Open LibraryOL8624752M
ISBN 101859961932
ISBN 109781859961933

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Book Description. Cell Proliferation and Apoptosis provides a detailed practical guide to cell proliferation and apoptosis detection methods. A novel approach combining both these areas allows important comparisons to be made. Cell Proliferation and Apoptosis 1st Edition by H.

Mehmet (Author), David Hughes (Editor), Huseyin Mehmet (Editor) & 0 more ISBN Cited by:   Cell Proliferation and Apoptosis. London: Taylor & Francis, Cell Proliferation and Apoptosis provides a detailed practical guide to cell proliferation and apoptosis detection methods.

A novel approach combining both these areas allows important comparisons to be by:   Cell Proliferation and Apoptosis provides a detailed practical guide to cell proliferation and apoptosis detection methods.

A novel approach combining both these areas allows important comparisons. Cell Proliferation and Apoptosis provides a detailed and novel practical guide to cell proliferation and apoptosis detection methods. Read more. miR‑18a‑5p promotes melanoma cell proliferation and inhibits apoptosis and autophagy by targeting EPHA7 signaling.

Authors: Yunlong Guo; Wenli Shi. miR‑‑5p regulates H9c2 cell proliferation and apoptosis under hypoxic conditions by targeting IL‑17A. Authors: Yin Ren; Ruanzhong Bao; Zhujun Guo. is a platform for academics to share research papers.

Introduction. A coordination and balance between cell proliferation and apoptosis is crucial for normal development and tissue-size homeostasis in the adult. Cancer results when clones of mutated cells survive and proliferate inappropriately, disrupting this balance.

In addition to apoptosis, quantification of cell proliferation can provide important additional information about the effect of a toxicant upon various immune cell populations.

In some cases, a toxicant may act as a mitogen pushing the immune cell into the different stages of the cell cycle. Cell Explorer™ cell labeling platform is a complete set of tools for tracking live cells. This platform is also widely used for sorting mixed populations of cells.

Cell Navigator™ cell staining platform is a complete set of tools for selective labeling subcellular structures of live, fixed and dead cells. The balance of cell proliferation and apoptosis is important for both development Cell Proliferation and Apoptosis book normal tissue homeostasis.

Cell proliferation is an increase in the number of cells as a result of growth and division. Cell proliferation is regulated by the cell cycle, which is divided into a series of phases.

Apoptosis, or programmed cell death, results in. NF-κB is considered a central regulator of inflammatory response, cell proliferation, and apoptosis. NF-κB overexpression induces antiapoptotic events, cell malignancy, and cancer-associated inflammation [45,].

NF-κB activity is closely coordinated to that of AP-1, affecting cell proliferation and differentiation []. The involvement of GRK2 in cancer cell proliferation and its counter-regulation of p53 have been suggested in breast cancer even if the underlying mechanism has not yet been elucidated.

Furthermore, the possibility to pharmacologically inhibit GRK2 to delay cancer cell proliferation has never been explored. We investigated this possibility by setting up a study that combined in vitro and in. Cell Proliferation, Differentiation and Apoptosis. (15) Miriam Huerta, Carla Angulo and Esther López-Bayghen.

Abstract. Tight control of the cell cycle in eukaryotic cells exists to control proliferation, differentiation or apoptosis. These processes model and shape tissue and organ relationships in multicellular organisms. Proliferation and apoptosis of cells in the trout optic nerve after optic nerve injury.

We detected the apoptosis and proliferative activity of cells in trout optic nerve after mechanical damage of the eye.

These processes prevailed on the ipsilateral side, since the number of TUNEL-labeled cells was times and the number of proliferating. Later on many oncogenes were found to be able to suppress apoptosis while stimulating cell proliferation. ‘Evasion of apoptosis’ or ‘resistance to apoptosis’ as a hallmark of cancer has become a doctrine of cancer biology, but there exist quite a few unclear or paradoxical issues.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Article A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis Lingli He,1,6 Liang Yuan,2,6 Wentao Yu,1 Yang Sun,1 Dan Jiang,1 Xiaodong Wang,2 Xue Feng,1 Zuoyun Wang,1 Jinjin Xu,1 Ruizeng Yang,1 Wenxiang Zhang,1 Hua Feng,4 Hang-zi Chen,5 Yi Arial Zeng,1 Lijian Hui,1 Qiao Wu,5 Yonglong Zhang,1,* and Lei Zhang1,2,3,7,* 1State Key Laboratory of Cell Biology.

In contrast to control of cell proliferation, DP1 and DP2 are not necessary for E2F1-induced apoptosis, indicating that E2F1-induced apoptosis is the second model of DP-independent E2F function.

The function of E2F1 to induce apoptosis is intuitively contradictory to its role in promoting cell : Hideyuki Komori, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Kiyoshi Ohtani. 2 Apoptosis, Cytotoxicity, and Cell Proliferation Manual How cells die: Apoptosis and other cell death pathways 1 How cells die: Apoptosis and other cell death pathways by Klaus Schulze-Osthoff Introduction Cell death is an essential part of normal development and continues into adulthood.

The. Specifically, we found Quercetin reduced the proliferation of B16 melanoma cells at 48 h as much or more than etoposide.

Although quercetin reduced the proportion of cells in the S and G2/M stages of the cell cycle, this could largely be explained by an increase in the subG1 population in quercetin-treated cells (suggesting apoptosis).

Oncology; OBJECTIVE: Phosphatase and tensin homologue deleted on chromosome ten (PTEN) regulates cell proliferation and apoptosis by inhibiting phosphatidylinositol-3 kinase (PI3K) and protein kinase (AKT) signaling. High expression of miR was associated with ovarian cancer.

This study aims to investigate whether miR regulates PTEN/PI3K/AKT signaling as well as its role in the. Cell health and growth can be determined by quantifying cell viability, proliferation, or apoptosis. Below, we compare some commonly used assays to help you determine which type is suitable for your experimental design.

Cell viability assays enumerate the ratio of live and dead cells in a population. Cell viability can simply be achieved by. These cells can develop to be cancerous cells.

Apoptosis is the programmed death of a cell. It occurs naturally in multicellular organisms and is used to regulate dead cells. Apoptosis occurs daily in human beings destroying naturally anywhere between 20 to 70 billion cells and those cells end up being replaced by newer cells. Apoptosis is a form of cell death characterized by several features including cell shrinkage, membrane blebbing, chromosome condensation, nuclear fragmentation, DNA laddering, and the eventual engulfment of the cell by phagosomes.

You can assay apoptosis using a number of different approaches. Overview. Introduction to apoptosis mechanisms. Cell Death - Autophagy, Apoptosis and Necrosis.

Edited by: Tobias M. Ntuli. ISBNPDF ISBNPublished This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but. This study aims to investigate the effects of glucose transport l (Glut1) gene on proliferation, differentiation, and apoptosis of colorectal cancer (CRC) cells by regulating the TGF‐β/PI3K‐AKT‐mTOR signaling pathway.

Immunohistochemistry was conducted to detect the positive Glut1 expression. TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis Cancer Med. Dec;8(17) doi: /cam Epub Oct Authors Libao Gong 1.

Adiponectin affects vascular smooth muscle cell proliferation and apoptosis through modulation of the mitofusinmediated Ras-Raf-Erk1/2 signaling pathway Mol Med Rep. Sep;12(3) doi: /mmr Epub Jun 8. Authors Wenbo Zhang 1.

HSC‐3 cells were treated with Res, Akt agonist (AL) and p16 inhibitor (SC79), and transfected with CBX7 mimics and inhibitor plasmids. The CCK‐8 assay was used to detect cell proliferation, flow cytometry was performed to assess cell cycle and apoptosis, and cell colonies and histone DNA level were also measured.

Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC). Certain studies have revealed that microRNAs play crucial roles in HBV-related HCC. The aim of this study was to investigate the effects of microRNA (miR) on HBV replication, cell proliferation and apoptosis in.

Trillin is a constituent of total Trillium Tschonoskii Maxim (TTM), which is extracted from TTM and displayed anti-tumor effect in many tumor cell lines. However, the anti-tumor mechanism of trillin is still unclear. This study demonstrated that trillin could dramatically inhibit hepatoma carcinoma cell proliferation, induce apoptosis and decrease migration and invasion through suppressing.

Apoptosis is a vital component of various processes including normal cell turnover, hormone-dependent atrophy, proper development and functioning of the immune system, chemical-induced cell death.

Essay On Apoptosis Words | 5 Pages. programed cell death associated with cancer cell proliferation inhibition, apoptosis is the most typical cell death mechanism, characterized by the activation of common caspases [Fulda and Debatin, ; Nakajima and Kuranaga, ].

Cell proliferation was determined using a Cell Counting Kit‑8 assay, whereas cell migration and invasion were analyzed using Transwell assays. Flow cytometric analysis was performed to determine the levels of cell apoptosis. The expression levels of GSTO1, Bax, caspase 3, JAK and STAT3 were analyzed using western blotting.

Apoptosis (from Ancient Greek ἀπόπτωσις, apóptōsis, "falling off") is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes and changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global [vague] mRNA decay.

Title: Mucosal T Cell Proliferation and Apoptosis in Inflammatory Bowel Disease VOLUME: 9 ISSUE: 5 Author(s):Andreas Sturm, Heitor S.P. de Souza and Claudio Fiocchi Affiliation:Department of Pathobiology,Lerner Research Institute and Department of Gastroenterology&Hepatology,The Cleveland Clinic Foundation, Euclid Avenue, Cleveland,OhioUSA.

Skeletal muscle plays a crucial role in physical activity and in regulating body energy and protein balance. Myoblast proliferation, differentiation, and apoptosis are indispensable processes for myoblast myogenesis.

Profilin 2a (PFN2a) is a ubiquitous actin monomer-binding protein and promotes lung cancer growth and metastasis through suppressing the nuclear localization of histone. To generate ADAMTS8 stable knockdown cells, MDA-MB cells were transfected with psi-H1-ADAMTS8siRNA plasmids. Cell counting kit-8 (CCK-8) assay, wound-healing assay, transwell assay and flow cytometry assay were employed to analyze the effects of ADAMTS8 on the proliferation, migration, invasion and apoptosis of BC cells.

We report that serum from these advanced cancer patients inhibits proliferation and enhances apoptosis of human prostate and colon cancer cells in vitro using cell growth and death assays (5‐bromo‐2′‐deoxyuridine incorporation, cell counting, DNA fragmentation).

Exercise‐mimicking electric pulse stimulation of human primary myotubes.Cell proliferation can be measured by MTT, XTT, SRB and trypan blue staining methods and For apoptosis determination, Use Annexin FITC/PI staining kit by flow cytometery or Fluorescent microscopy.Cell Counting Kit-8 (CCK-8) assay, colony formation assay, and flow cytometry were employed to analyze the proliferation and apoptosis of cells.

Thereafter, the target proteins of miRa were predicted using TargetScan, a website for miRNA target gene prediction, and the interaction between miRa and the target genes was detected through the.

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